Debrisoquin hemisulfate

• CAT Number: R007285
• CAS Number: 581-88-4
• Molecular Formula: C10H13N3.1/2H2O4S
• Molecular Weight: 224.27
• Purity: ≥95%
• IUPAC Name: 3,4-dihydro-1H-isoquinoline-2-carboximidamide;sulfuric acid
• InChI: InChI=1S/2C10H13N3.H2O4S/c2*11-10(12)13-6-5-8-3-1-2-4-9(8)7-13;1-5(2,3)4/h2*1-4H,5-7H2,(H3,11,12);(H2,1,2,3,4)
• InChIKey: CAYGYVYWRIHZCQ-UHFFFAOYSA-N
• SMILES: C1CN(CC2=CC=CC=C21)C(=N)N.C1CN(CC2=CC=CC=C21)C(=N)N.OS(=O)(=O)O

Debrisoquin Hemisulfate(CAT: R007285) is a pharmaceutical compound primarily used in Cardiovascular Disease Research as a prototype drug to study cytochrome P450 enzyme activity, particularly CYP2D6. It acts as an antihypertensive agent, lowering blood pressure by inhibiting the central nervous system’s sympathetic output. However, its key use in research is to evaluate drug metabolism due to its selective metabolism by the CYP2D6 enzyme, which exhibits genetic polymorphism in humans. This makes Debrisoquin an important tool in pharmacogenetics, helping to assess individual responses to drugs and improve personalized medicine approaches, especially in hypertension treatment.