Decarboxylated S-Adenosylmethionine Sulfate Salt

• CAT Number: R063209
• CAS Number: 67380-81-8
• Molecular Formula: C₁₄H₂₄N₆O₇S₂ •H₂SO₄
• Molecular Weight: 452.52
• Purity: ≥95%
• Synonyms: 5’-[(3-aminopropyl)methylsulfonio]-5’-deoxy-adenosine Sulfate Salt sulfate(salt) (1:1:1);?(-)-S-Adenosyl-(5’)-3-methylthiopropylamine Sulfate Salt; Decarboxylated AdoMet Sulfate Salt; S-Adenosyl-3-methylthiopropylamine Sulfate Salt; S-Adenosyl-L-meth
• Storage: -20°C
• IUPAC Name: 3-aminopropyl-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulfanium;hydrogen sulfate;sulfuric acid
• InChI: InChI=1S/C14H23N6O3S.2H2O4S/c1-24(4-2-3-15)5-8-10(21)11(22)14(23-8)20-7-19-9-12(16)17-6-18-13(9)20;2*1-5(2,3)4/h6-8,10-11,14,21-22H,2-5,15H2,1H3,(H2,16,17,18);2*(H2,1,2,3,4)/q+1;;/p-1/t8-,10-,11-,14-,24?;;/m1../s1
• InChIKey: NZCXDNATCGDLIE-RGBAOSDGSA-M
• SMILES: C[S+](CCCN)CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O.OS(=O)(=O)O.OS(=O)(=O)[O-]

Decarboxylated S-Adenosylmethionine Sulfate Salt(CAT: R063209) is a derivative of S-adenosylmethionine (SAM), an essential biological molecule involved in methyl group transfers. In its decarboxylated form, this compound plays a crucial role in polyamine biosynthesis, acting as a donor of aminopropyl groups during the formation of polyamines such as spermidine and spermine, which are critical for cell growth and differentiation. The sulfate salt enhances its solubility and stability, making it more suitable for biochemical research and pharmaceutical applications. It is often studied in the context of cellular metabolism, enzymatic reactions, and its potential therapeutic applications in neurodegenerative diseases and cancer.