DECYL GLUCOSIDE

• CAT Number: M104276
• CAS Number: 141464-42-8
• Molecular Formula: C16H32O6
• Molecular Weight: 320.42
• Purity: ≥95%
• Synonyms: Decyl D-glucopyranoside; (3R,4S,5S,6R)-2-(Decyloxy)-6-(hydroxymethyl)tetrahydro-2H-Pyran-3,4,5-triol; Decyl D-glucoside
• Storage: Store at -20°C
• IUPAC Name: (3R,4S,5S,6R)-2-decoxy-6-(hydroxymethyl)oxane-3,4,5-triol
• InChI: InChI=1S/C16H32O6/c1-2-3-4-5-6-7-8-9-10-21-16-15(20)14(19)13(18)12(11-17)22-16/h12-20H,2-11H2,1H3/t12-,13-,14+,15-,16?/m1/s1
• InChIKey: JDRSMPFHFNXQRB-IWQYDBTJSA-N
• SMILES: CCCCCCCCCCOC1C(C(C(C(O1)CO)O)O)O

Decyl glucoside (Cat No.:M104276) is a mild and biodegradable nonionic surfactant derived from natural sources, typically coconut or palm kernel oil and glucose from corn starch. It is widely used in personal care and household products as a gentle cleansing and foaming agent. Due to its plant-based origin and low potential for skin irritation, it is often chosen for sensitive skin formulations. Decyl glucoside is found in products like shampoos, body washes, and facial cleansers, contributing to their effective cleaning while maintaining a gentle and environmentally friendly profile. Its mild nature makes it suitable for various applications.

Reference

1. Current Opinion in Colloid & Interface Science.2001 May 1;6(2):148-59.Natural surfactants.Holmberg K.

The ever-increasing environmental concern about surfactants triggers an interest in natural surfactant. This review, which has an emphasis on work published since 1998, covers three categories of natural surfactants: amphiphiles produced by yeast or bacteria, amphiphiles containing a natural polar headgroup and amphiphiles containing a natural hydrophobic tail. Microorganisms produce both high molecular weight and low molecular weight surfactants. Only the low molecular weight compounds are included in the review. Sugars and amino acids are the two most important examples of surfactant polar headgroups of natural origin. The research is particularly intense in the area of sugar surfactants and the review covers three types: alkylglucosides, alkylglucamides and sugar esters. Surfactants based on two types of natural hydrophobic tails are included: fatty acid monoethanolamides and sterol ethoxylates. Routes of preparation as well as physico-chemical properties  are discussed for the surfactants prepared by organic synthesis.

2. International journal of toxicology. 2013 Sep;32(5_suppl):22S-48S.Safety assessment of decyl glucoside and other alkyl glucosides as used in cosmetics.Fiume MM, Heldreth B, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler D, Marks Jr JG, Shank RC, Slaga TJ, Snyder PW.

The Cosmetic Ingredient Review (CIR) Expert Panel assessed the safety of 19 alkyl glucosides as used in cosmetics and concluded that these ingredients are safe in the present practices of use and concentration when formulated to be nonirritating. Most of these ingredients function as surfactants in cosmetics, but some have additional functions as skin-conditioning agents, hair-conditioning agents, or emulsion stabilizers. The Panel reviewed the available animal and clinical data on these ingredients. Since glucoside hydrolases in human skin are likely to break down these ingredients to release their respective fatty acids and glucose, the Panel also reviewed CIR reports on the safety of fatty alcohols and were able to extrapolate data from those previous reports to support safety.