Deferasirox Fe3(addition) chelate

• CAT Number: I013951
• CAS Number: 554435-83-5
• Molecular Formula: C₂₁H₁₂FeN₃O₄
• Molecular Weight: 426.18
• Purity: ≥95%
• Target: Anti-infection
• Solubility: 10 mM in DMSO
• IUPAC Name: 4-[3,5-bis(2-oxidophenyl)-1,2,4-triazol-1-yl]benzoate;iron(3+)
• InChI: InChI=1S/C21H15N3O4.Fe/c25-17-7-3-1-5-15(17)19-22-20(16-6-2-4-8-18(16)26)24(23-19)14-11-9-13(10-12-14)21(27)28;/h1-12,25-26H,(H,27,28);/q;+3/p-3
• InChIKey: ABQALTGEPFNCIY-UHFFFAOYSA-K
• SMILES: C1=CC=C(C(=C1)C2=NN(C(=N2)C3=CC=CC=C3[O-])C4=CC=C(C=C4)C(=O)[O-])[O-].[Fe+3]

Deferasirox Fe³⁺ (addition) chelate(CAT: I013951) is a stable complex formed between Deferasirox, an oral iron chelator, and ferric ions (Fe³⁺). Deferasirox selectively binds to excess Fe³⁺ in the bloodstream, forming a chelate that is excreted primarily through bile and feces, effectively reducing iron overload. This mechanism is particularly beneficial in managing chronic iron overload conditions, such as those resulting from frequent blood transfusions in patients with thalassemia, sickle cell disease, and myelodysplastic syndromes. In hematology and metabolic disease research, the Deferasirox-Fe³⁺ chelate is vital for studying iron metabolism and developing therapies for iron-related disorders.