For research use only. Not for therapeutic Use.
Deferasirox Fe³⁺ Chelate(CAT: I004064) represents the stable complex formed between Deferasirox, an oral iron chelator, and ferric ions (Fe³⁺). Deferasirox functions by binding excess ferric ions with high affinity, forming a 2:1 ligand-to-metal complex, which facilitates iron excretion primarily via feces. This compound is extensively used in research on iron-overload disorders, such as thalassemia and hereditary hemochromatosis, as well as in understanding iron homeostasis and its pathological implications. The Fe³⁺ chelate is pivotal in studies exploring chelation efficacy, pharmacokinetics, and therapeutic mechanisms in conditions associated with iron toxicity.
| Catalog Number | I004064 |
| CAS Number | 554435-83-5 |
| Synonyms | 4-[3,5-bis(2-oxidophenyl)-1,2,4-triazol-1-yl]benzoate;iron(3+) |
| Molecular Formula | C21H12FeN3O4 |
| Purity | ≥95% |
| Target | Ferroptosis; Bacterial |
| Solubility | 10 mM in DMSO |
| Storage | Store at -20°C |
| IUPAC Name | 4-[3,5-bis(2-oxidophenyl)-1,2,4-triazol-1-yl]benzoate;iron(3+) |
| InChI | InChI=1S/C21H15N3O4.Fe/c25-17-7-3-1-5-15(17)19-22-20(16-6-2-4-8-18(16)26)24(23-19)14-11-9-13(10-12-14)21(27)28;/h1-12,25-26H,(H,27,28);/q;+3/p-3 |
| InChIKey | ABQALTGEPFNCIY-UHFFFAOYSA-K |
| SMILES | C1=CC=C(C(=C1)C2=NN(C(=N2)C3=CC=CC=C3[O-])C4=CC=C(C=C4)C(=O)[O-])[O-].[Fe+3] |
