Defluoro 8-Hydroxy Flumazenil (Impurity)

• CAT Number: R023550
• CAS Number: 131666-45-0
• Molecular Formula: C15H15N3O4
• Molecular Weight: 301.302
• Purity: ≥95%
• Synonyms: 5,6-Dihydro-8-hydroxy-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic Acid Ethyl Ester; USP Flumazenil Related Compound B
• Storage: -20°C
• IUPAC Name: ethyl 8-hydroxy-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
• InChI: InChI=1S/C15H15N3O4/c1-3-22-15(21)13-12-7-17(2)14(20)10-6-9(19)4-5-11(10)18(12)8-16-13/h4-6,8,19H,3,7H2,1-2H3
• InChIKey: PCCARNSSXAGDHQ-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CC(=C3)O)C

Defluoro 8-Hydroxy Flumazenil is a derivative of flumazenil, a benzodiazepine antagonist commonly used to reverse the effects of benzodiazepines in cases of overdose. This compound features a hydroxyl group at the 8-position and lacks a fluorine atom, which may alter its binding affinity and pharmacokinetic properties. Research indicates that this modification could enhance its selectivity and efficacy in targeting specific benzodiazepine receptors. Defluoro 8-Hydroxy Flumazenil is being explored for its potential to provide safer and more effective treatment options for managing benzodiazepine overdose and in applications related to anesthetic recovery, highlighting its significance in pharmacological research.