DEG-35

• CAT Number: I047240
• Molecular Weight: 443.45
• Purity: ≥95%

DEG-35 is a cereblon-dependent degrader of IKZF2 and casein kinase 1α (CK1α). It blocks cell growth and delays leukemia progression in murine and human acute myeloid leukemia (AML) mouse models.

Reference

[1] Park SM, et al. Cancer Cell. 2023 Apr 10;41(4):726-739.e11.