Dehydro Amlodipine Fumarate

• CAT Number: C000657
• CAS Number: 2138811-33-1
• Molecular Formula: C₂₀H₂₃ClN₂O₅ • ( C₄H₄O₄)
• Molecular Weight: 522.94
• Purity: ≥95%
• Synonyms: 3-Ethyl 5-methyl 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methylpyridine-3,5-dicarboxylate (2E)-But-2-enedioic Acid
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Appearance: White to Off-White Solid
• Storage: -20°C, Hygroscopic
• IUPAC Name: (E)-but-2-enedioic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methylpyridine-3,5-dicarboxylate
• InChI: InChI=1S/C20H23ClN2O5.C4H4O4/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;5-3(6)1-2-4(7)8/h5-8H,4,9-11,22H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
• InChIKey: BWAQLJHPVPAANJ-WLHGVMLRSA-N
• SMILES: CCOC(=O)C1=C(C(=C(N=C1COCCN)C)C(=O)OC)C2=CC=CC=C2Cl.C(=CC(=O)O)C(=O)O

Dehydro Amlodipine Fumarate (Cat No.:C000657) is a derivative of amlodipine, an antihypertensive medication used to treat high blood pressure and angina. The dihydro modification alters its chemical structure, potentially influencing its pharmacological properties. Amlodipine functions by blocking calcium channels, relaxing blood vessels, and improving blood flow. Research on Dehydro Amlodipine Fumarate may explore its effects on calcium channel inhibition, cardiovascular responses, and potential applications in managing cardiovascular conditions.

Reference

Li, Jie, et al.: Yaowu Fenxi Zazhi, 35(11),В 1999-2005 (2015)