For research use only. Not for therapeutic Use.
Dehydronuciferine is isolated from the leaves of Nelumbo nucifera Gaertn, a acetylcholinesterase (AChE) inhibitor with an IC50 of 25 μg/mL[1].
Catalog Number | I018231 |
CAS Number | 7630-74-2 |
Synonyms | 15,16-dimethoxy-10-methyl-10-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(17),2,4,6,8,13,15-heptaene |
Molecular Formula | C19H19NO2 |
Purity | ≥95% |
InChI | InChI=1S/C19H19NO2/c1-20-9-8-13-11-16(21-2)19(22-3)18-14-7-5-4-6-12(14)10-15(20)17(13)18/h4-7,10-11H,8-9H2,1-3H3 |
InChIKey | JBGSWIBJAGBGOP-UHFFFAOYSA-N |
SMILES | CN1CCC2=CC(=C(C3=C2C1=CC4=CC=CC=C43)OC)OC |
Reference | [1]. Yang, et al. Synthesis and structure-activity relationship of nuciferine derivatives as potential acetylcholinesterase inhibitors. Medicinal Chemistry Research June 2014, Volume 23, Issue 6, pp 3178–3186 |