Dehydrotrametenolic acid

• CAT Number: I018244
• CAS Number: 6879-05-6
• Molecular Formula: C₃₁H₄₈O₃
• Molecular Weight: 468.71
• Purity: ≥95%
• Target: Caspase
• IUPAC Name: (2R)-2-[(3S,5R,10S,13R,14R,17R)-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methyl-5-methylideneheptanoic acid
• InChI: InChI=1S/C31H48O3/c1-19(2)20(3)9-10-21(27(33)34)22-13-17-31(8)24-11-12-25-28(4,5)26(32)15-16-29(25,6)23(24)14-18-30(22,31)7/h11,14,19,21-22,25-26,32H,3,9-10,12-13,15-18H2,1-2,4-8H3,(H,33,34)/t21-,22-,25+,26+,29-,30-,31+/m1/s1
• InChIKey: ONFPYGOMAADWAT-OXUZYLMNSA-N
• SMILES: CC(C)C(=C)CC[C@H]([C@H]1CC[C@@]2([C@@]1(CC=C3C2=CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)C)C(=O)O

Dehydrotrametenolic acid (Cat No.:I018244) is a natural triterpenoid compound derived from medicinal mushrooms. It exhibits various pharmacological activities, including anti-inflammatory, antioxidant, antitumor, and immunomodulatory effects. Dehydrotrametenolic acid has been investigated for its potential therapeutic applications in the treatment of cancer, cardiovascular diseases, and liver disorders. It has shown promising anticancer activity by inhibiting cell proliferation, inducing apoptosis, and suppressing tumor growth in preclinical studies. Additionally, dehydrotrametenolic acid has demonstrated anti-inflammatory effects by modulating the production of inflammatory mediators and reducing oxidative stress. Its immunomodulatory properties suggest potential applications in immune-related disorders.

Reference

[1]. Kang HM, et al. Dehydrotrametenolic acid selectively inhibits the growth of H-ras transformed rat2 cells and induces apoptosis through caspase-3 pathway. Life Sci. 2006 Jan 2;78(6):607-13.