Delpazolid

• CAT Number: I006020
• CAS Number: 1219707-39-7
• Molecular Formula: C14H17FN4O3
• Molecular Weight: 308.31
• Purity: ≥95%
• Synonyms: Delpazolid; LCB01-0371; LCB 01-0371; LCB-01-0371; LCB010371; LCB 010371; LCB-010371.;(5R)-3-[3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one
• Target: Bacterial
• Solubility: Soluble in DMSO
• Storage: 0 - 4°C for short term ,or -20 °C for long term
• IUPAC Name: (5R)-3-[3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one
• InChI: InChI=1S/C14H17FN4O3/c1-17-4-5-18(9-16-17)13-3-2-10(6-12(13)15)19-7-11(8-20)22-14(19)21/h2-3,6,9,11,20H,4-5,7-8H2,1H3/t11-/m1/s1
• InChIKey: QLUWQAFDTNAYPN-LLVKDONJSA-N
• SMILES: CN1CCN(C=N1)C2=C(C=C(C=C2)N3C[C@@H](OC3=O)CO)F

Delpazolid（Cat No.:I006020）is an oxazolidinone antibiotic with potent activity against Gram-positive bacteria, including multi-drug-resistant strains such as vancomycin-resistant enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). It works by inhibiting bacterial protein synthesis through binding to the 23S rRNA of the 50S ribosomal subunit. Delpazolid is notable for its low toxicity and favorable pharmacokinetics, making it a promising candidate for treating serious infections. It is undergoing clinical trials to assess its safety and efficacy in treating various resistant infections, offering an important alternative in the fight against antibiotic resistance.