Demethylbleomycin A2 (Technical Grade)

• CAT Number: C000395
• CAS Number: 41089-03-6
• Molecular Formula: C₅₄H₈₁N₁₇O₂₁S₃
• Molecular Weight: 1400.52
• Purity: ≥95%
• Synonyms: Bleomycin DM-A2, N1-[3-(Methylthio)propyl]bleomycinamide; (2R,3S,4S,5R,6R)-2-(((2R,3S,4R,5S,6S)-2-((1R,2S)-2-(6-Amino-2-((S)-3-amino-1-(((S)-2,3-diamino-3-oxopropyl)amino)-3-oxopropyl)-5-methylpyrimidine-4-carboxamido)-3-(((2R,3S,4S)-3-hydroxy-5-(((3R)-3-hydroxy-1-((2-(4-((3-(methylthio)propyl)carbamoyl)-[2,4′-bithiazol]-2′-yl)ethyl)amino)-1-oxobutan-2-yl)amino)-4-methyl-5-oxopentan-2-yl)amino)-1-(1H-imidazol-4-yl)-3-oxopropoxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl Carbamate
• Target: Antibiotic
• Solubility: Acetonitrile (Slightly), Water (Very Slightly)
• Appearance: White to Off-White Solid
• Storage: -20°C, Hygroscopic

Demethylbleomycin A2 is a derivative of Bleomycin ,a glycopeptide antibiotic.

Reference

Carter, Barbara J.et al.: J. Biol. Chem., 265,В 4193(1990); Tanaka, Wataru., et al.: Heterocycles, 13,В 469 (1979); Takita, Tomohisa; et al.: J. Antibiot.,В В 26,В 252(1973);Byrnes, Robert W., et al.: Cancer Res.,В В 50,В 5275(1990);