Denosumab

For research use only. Not for therapeutic Use.

  • Cancer Immunotherapy,
  • CAT Number: I043755
  • CAS Number: 615258-40-7
  • Molecular Formula: C6404H9908N1724O2004S50
  • Molecular Weight: 144716.86
  • Purity: ≥95%
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Denosumab is a human monoclonal antibody binding to, and inhibiting, the receptor activator of RANKL (TNFSF11). Denosumab can reduce the risk of vertebral, nonvertebral and hip fractures[1], also has anti-cancer activity[2].


Catalog Number I043755
CAS Number 615258-40-7
Molecular Formula C6404H9908N1724O2004S50
Purity ≥95%
Reference

[1]. Moen MD, et al. Denosumab: a review of its use in the treatment of postmenopausal osteoporosis. Drugs Aging. 2011;28(1):63-82.
 [Content Brief]

[2]. Chawla S, et al. Denosumab in patients with giant-cell tumour of bone: a multicentre, open-label, phase 2 study. Lancet Oncol. 2019;20(12):1719-1729.
 [Content Brief]

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