For research use only. Not for therapeutic Use.
Deoxynivalenol (DON), also known as vomitoxin, is a type of mycotoxin produced by Fusarium species of fungi, commonly found in contaminated grains such as wheat, corn, and barley. It poses significant health risks to both humans and animals, leading to symptoms like nausea, vomiting, diarrhea, and immune suppression when ingested. In livestock, exposure to Deoxynivalenol can result in reduced feed intake and growth performance. Due to its toxic nature, DON is closely monitored in food and feed products, with strict regulations in place to limit its levels and ensure safety.
Catalog Number | R058378 |
CAS Number | 51481-10-8 |
Synonyms | (3α,7α)-12,13-Epoxy-3,7,15-trihydroxytrichothec-9-en-8-one; 4-Deoxynivalenol; 4-Desoxynivalenol; DON; Dehydronivalenol; NSC 269144; Vomitoxin; |
Molecular Formula | C15H20O6 |
Purity | ≥95% |
Target | Immunology and Inflammatory Disease Models |
Solubility | Soluble in DMSO > 10 mM |
Storage | Store at +4°C |
IUPAC Name | (1R,2R,3S,7R,9R,10R,12S)-3,10-dihydroxy-2-(hydroxymethyl)-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-one |
InChI | InChI=1S/C15H20O6/c1-7-3-9-14(5-16,11(19)10(7)18)13(2)4-8(17)12(21-9)15(13)6-20-15/h3,8-9,11-12,16-17,19H,4-6H2,1-2H3/t8-,9-,11-,12-,13-,14-,15+/m1/s1 |
InChIKey | LINOMUASTDIRTM-QGRHZQQGSA-N |
SMILES | CC1=CC2C(C(C1=O)O)(C3(CC(C(C34CO4)O2)O)C)CO |