For research use only. Not for therapeutic Use.
DEPTOR-IN-1 is a novel putative DEPTOR inhibitor with a Kd value of 9.3 μM.
| Catalog Number | I045335 |
| CAS Number | 2615911-12-9 |
| Synonyms | 2-(3,4-dichlorophenyl)-9-[(3-fluorophenyl)methyl]-3-hydroxy-8,10-dihydropyrano[2,3-f][1,3]benzoxazin-4-one |
| Molecular Formula | C24H16Cl2FNO4 |
| Purity | ≥95% |
| InChI | InChI=1S/C24H16Cl2FNO4/c25-18-6-4-14(9-19(18)26)23-22(30)21(29)16-5-7-20-17(24(16)32-23)11-28(12-31-20)10-13-2-1-3-15(27)8-13/h1-9,30H,10-12H2 |
| InChIKey | YHKREPOFPNSZAL-UHFFFAOYSA-N |
| SMILES | C1C2=C(C=CC3=C2OC(=C(C3=O)O)C4=CC(=C(C=C4)Cl)Cl)OCN1CC5=CC(=CC=C5)F |
| Reference | [1]. Hou Y, et al. Design, Synthesis, and Biological Evaluation of Icaritin Derivatives as Novel Putative DEPTOR Inhibitors for Multiple Myeloma Treatment. J Med Chem. 2021 Oct 28;64(20):14942-14954. |
