For research use only. Not for therapeutic Use.
Deruxtecan analog 2（Cat No.:I042948）is a synthetic compound designed as a derivative of deruxtecan, a targeted chemotherapy agent. It features a potent cytotoxic payload linked to a monoclonal antibody that specifically targets tumor cells, particularly those overexpressing certain tumor-associated antigens. This analog is being investigated in cancer research for its potential to improve efficacy and reduce systemic toxicity by delivering the cytotoxic drug directly to cancer cells. It holds promise in treating various cancers, including breast and gastrointestinal cancers, by utilizing advanced drug-delivery mechanisms for enhanced therapeutic outcomes.
| CAS Number | 1599440-10-4 |
| Synonyms | 2-amino-N-[[2-[[(10S,23S)-10-ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl]amino]-2-oxoethoxy]methyl]acetamide |
| Molecular Formula | C29H30FN5O7 |
| Purity | ≥95% |
| IUPAC Name | 2-amino-N-[[2-[[(10S,23S)-10-ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl]amino]-2-oxoethoxy]methyl]acetamide |
| InChI | InChI=1S/C29H30FN5O7/c1-3-29(40)17-6-21-26-15(9-35(21)27(38)16(17)10-42-28(29)39)25-19(33-23(37)11-41-12-32-22(36)8-31)5-4-14-13(2)18(30)7-20(34-26)24(14)25/h6-7,19,40H,3-5,8-12,31H2,1-2H3,(H,32,36)(H,33,37)/t19-,29-/m0/s1 |
| InChIKey | DOLQXGLTQNTQEP-SLQAJWMNSA-N |
| SMILES | CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5[C@H](CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)NC(=O)COCNC(=O)CN)O |
