Des(1-cyclohexanol) Venlafaxine-d6

• CAT Number: R049370
• CAS Number: 1330046-00-8
• Molecular Formula: C11H17NO
• Molecular Weight: 185.3
• Purity: ≥95%
• Synonyms: 4-Methoxy-N,N-(dimethyl-d6)benzeneethanamine; p-Methoxy-N,N-(dimethyl-d6)?phenethylamine; N,N-(Dimethyl-d6)-2-(p-anisyl)ethylamine; N,N-(Dimethyl-d6)-4-methoxyphenethylamine
• Storage: -20°C
• IUPAC Name: 2-(4-methoxyphenyl)-N,N-bis(trideuteriomethyl)ethanamine
• InChI: InChI=1S/C11H17NO/c1-12(2)9-8-10-4-6-11(13-3)7-5-10/h4-7H,8-9H2,1-3H3/i1D3,2D3
• InChIKey: BGSZBHCYLIHECZ-WFGJKAKNSA-N
• SMILES: CN(C)CCC1=CC=C(C=C1)OC

Des(1-cyclohexanol) Venlafaxine-d6 is a deuterated form of a metabolite of venlafaxine, an antidepressant used to treat major depressive disorder, anxiety, and panic disorder. In this compound, six hydrogen atoms are replaced with deuterium, enhancing its utility in pharmacokinetic and metabolic studies. The deuterium labeling allows for precise tracking and differentiation in mass spectrometry and NMR spectroscopy, facilitating detailed analysis of the metabolite’s absorption, distribution, metabolism, and excretion. Despite the isotopic modification, it retains the same biological properties, making it valuable for research into venlafaxine’s metabolic pathways.