Desbutyl Bumetanide

• CAT Number: R008619
• CAS Number: 28328-54-3
• Molecular Formula: C13H12N2O5S
• Molecular Weight: 308.308
• Purity: ≥95%
• Synonyms: 3-Amino-5-(aminosulfonyl)-4-phenoxy-benzoic Acid; 3-Amino-4-phenoxy-5-sulfamoylbenzoic Acid; Desbutylbumetanide; PF 1578; USP?Bumetanide Related Compound A, Bumetanide impurity B (EP)
• Storage: -20°C
• IUPAC Name: 3-amino-4-phenoxy-5-sulfamoylbenzoic acid
• InChI: InChI=1S/C13H12N2O5S/c14-10-6-8(13(16)17)7-11(21(15,18)19)12(10)20-9-4-2-1-3-5-9/h1-7H,14H2,(H,16,17)(H2,15,18,19)
• InChIKey: GVQZPZSQRCXSJI-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)OC2=C(C=C(C=C2S(=O)(=O)N)C(=O)O)N

Desbutyl Bumetanide is a metabolite of the diuretic drug Bumetanide, commonly used in pharmaceutical research to study its pharmacokinetics and metabolism. Lacking the butyl group present in the parent compound, Desbutyl Bumetanide retains some of the biological activity associated with loop diuretics, influencing electrolyte transport in the kidneys. It is often utilized in research related to renal function and drug efficacy, particularly in studies focusing on fluid retention disorders such as heart failure and hypertension.