For research use only. Not for therapeutic Use.
Desbutyl Lumefantrine is a metabolite of lumefantrine with antimalarial activity[1].
| Catalog Number | R043373 |
| CAS Number | 355841-11-1 |
| Synonyms | 2-(butylamino)-1-[(9Z)-2,7-dichloro-9-[(4-chlorophenyl)methylidene]fluoren-4-yl]ethanol |
| Molecular Formula | C26H24Cl3NO |
| Purity | ≥95% |
| InChI | InChI=1S/C26H24Cl3NO/c1-2-3-10-30-15-25(31)24-14-19(29)13-23-21(11-16-4-6-17(27)7-5-16)22-12-18(28)8-9-20(22)26(23)24/h4-9,11-14,25,30-31H,2-3,10,15H2,1H3/b21-11- |
| InChIKey | YLBUTQNEBVPTES-NHDPSOOVSA-N |
| SMILES | CCCCNCC(C1=CC(=CC2=C1C3=C(C2=CC4=CC=C(C=C4)Cl)C=C(C=C3)Cl)Cl)O |
| Reference | [1]. Wong RP, et al. Desbutyl-lumefantrine is a metabolite of lumefantrine with potent in vitro antimalarial activity that may influence artemether-lumefantrine treatment outcome. Antimicrob Agents Chemother. 2011 Mar;55(3):1194-8. |
