Desfuroyl Ceftiofur Dimer (>90%)

• CAT Number: C000394
• CAS Number: 120905-00-2
• Molecular Formula: C₂₈H₂₈N₁₀O₁₀S₆
• Molecular Weight: 856.97
• Purity: ≥95%
• Synonyms: (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[[[[(6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]dithio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
• Solubility: Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
• Appearance: Off-White to Pale Beige Solid
• Storage: -20°C, Hygroscopic
• IUPAC Name: (6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[[(6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyldisulfanyl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• InChI: InChI=1S/C28H28N10O10S6/c1-47-35-13(11-7-51-27(29)31-11)19(39)33-15-21(41)37-17(25(43)44)9(3-49-23(15)37)5-53-54-6-10-4-50-24-16(22(42)38(24)18(10)26(45)46)34-20(40)14(36-48-2)12-8-52-28(30)32-12/h7-8,15-16,23-24H,3-6H2,1-2H3,(H2,29,31)(H2,30,32)(H,33,39)(H,34,40)(H,43,44)(H,45,46)/b35-13+,36-14+/t15-,16-,23-,24-/m1/s1
• InChIKey: PYRWVZOVUOUHKK-AFQMBUBWSA-N
• SMILES: CO/N=C(/C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)O)CSSCC3=C(N4C(=O)[C@H]([C@H]4SC3)NC(=O)/C(=N/OC)/C5=CSC(=N5)N)C(=O)O)\C6=CSC(=N6)N

Desfuroyl Ceftiofur Dimer (>90%)（Cat No.:C000394）is a metabolite of Ceftiofur, a third-generation cephalosporin antibiotic used in veterinary medicine to treat bacterial infections in animals. This compound forms when Ceftiofur is metabolized in the body, typically in livestock, and is used to assess the residue levels of Ceftiofur in animal products. The dimer form, with a purity greater than 90%, is significant for its high stability and longer half-life compared to the parent drug, making it important in residue analysis and ensuring compliance with food safety regulations.

Reference

Donaldson, S.C. et al.: Appl. Environ. Microbiol., 72, 3940 (2006); Yancey, R.J. et al.: Am. J. Vet. Res., 48, 1050 (1987);