Desloratadine-d4

• CAT Number: R003581
• CAS Number: 381727-29-3
• Molecular Formula: C19H19ClN2
• Molecular Weight: 314.85
• Purity: ≥95%
• Synonyms: 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine-d4; Aerius-d4; Allex-d4; Azomyr-d4; Clarinex-d4; Descarboethoxyloratadine-d4; NSC 675447-d4; Neoclarityn-d4; Opulis-d4; Sch 34117-d4
• Storage: Store at RT
• IUPAC Name: 13-chloro-2-(2,2,6,6-tetradeuteriopiperidin-4-ylidene)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene
• InChI: InChI=1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2/i10D2,11D2
• InChIKey: JAUOIFJMECXRGI-MKQHWYKPSA-N
• SMILES: [2H]C1(CC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC(N1)([2H])[2H])[2H]

Desloratadine-d4（Cat No.:R003581） is a deuterated version of Desloratadine, where four hydrogen atoms are replaced with deuterium. This isotopic enhancement increases the stability of the molecule, making it particularly useful for pharmacokinetic and metabolic studies. Desloratadine is an antihistamine used to treat allergy symptoms such as sneezing, runny nose, and itchy eyes. The deuterated form, Desloratadine-d4, allows researchers to more accurately trace the drug’s absorption, distribution, metabolism, and excretion processes, thereby gaining a clearer understanding of its efficacy and safety.