For research use only. Not for therapeutic Use.
Deslorelin(CAT: I006021) is a gonadotropin-releasing hormone super-agonist (GnRH agonist) also known as an LHRH agonist. It stops the production of sex hormones (testosterone and oestrogen). It is currently approved for use in veterinary medicine. This product is used for medical research and development and other scientific research purposes.
| Catalog Number | I006021 |
| CAS Number | 82318-06-7 |
| Synonyms | Deslorelin Acetate; H 4065; Somagard; Tryptal; GNRH (D-Trp6,pro9-net). brand name Ovuplant. Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHEt.;(S)-1-((3S,6S,9S,12S,15R,18S,21S)-3-((1H-imidazol-5-yl)methyl)-6,15-bis((1H-indol-3-yl)methyl)-21-(3-((diaminometh |
| Molecular Formula | C66H87N17O14 |
| Purity | ≥95% |
| Solubility | Soluble in DMSO, not in water |
| Storage | 0 - 4°C for short term ,or -20 °C for long term |
| Reference | </br>1:Effect of deslorelin acetate treatment in oocyte recovery and in vitro embryo production in domestic cats. Ackermann CL, Trevisol E, Crocomo LF, Rascado TD, Volpato R, Guaitolini CR, Lopes C, Costa TA, Lopes MD.J Feline Med Surg. 2016 Dec 2. pii: 1098612X16680697. [Epub ahead of print] PMID: 27913778 </br>2:Use of deslorelin acetate implants to control aggression in a multi-male group of Rock Hyrax (Procavia capensis). Raines JA, Fried JJ.Zoo Biol. 2016 May;35(3):201-4. doi: 10.1002/zoo.21290. Epub 2016 May 3. PMID: 27142595 </br>3:COMPARISON OF TWO 4.7-MILLIGRAM TO ONE 9.4-MILLIGRAM DESLORELIN ACETATE IMPLANTS ON EGG PRODUCTION AND PLASMA PROGESTERONE CONCENTRATIONS IN JAPANESE QUAIL (COTURNIX COTURNIX JAPONICA). Petritz OA, Guzman DS, Hawkins MG, Kass PH, Conley AJ, Paul-Murphy J.J Zoo Wildl Med. 2015 Dec;46(4):789-97. doi: 10.1638/2014-0210.1. PMID: 26667535 </br>4:Expression of angiogenic factors and luteinizing hormone receptors in the corpus luteum of mares induced to ovulate with deslorelin acetate. Maia VN, Batista AM, Cunha Neto S, Silva DM, Adrião M, Wischral A.Theriogenology. 2016 Feb;85(3):461-5. doi: 10.1016/j.theriogenology.2015.09.025. Epub 2015 Sep 18. PMID: 26476595 </br>5:Influence of ovariohysterectomy and deslorelin acetate on the spontaneous activity of the rabbit urinary bladder in vitro. Bujok J, Wincewicz E, Czerski A, Zawadzki W.Theriogenology. 2016 Feb;85(3):441-6. doi: 10.1016/j.theriogenology.2015.09.018. Epub 2015 Sep 16. PMID: 26474688 </br>6:Use of Deslorelin Acetate Implants to Mitigate Aggression in Two Adult Male Domestic Turkeys (Meleagris gallopavo) and Correlating Plasma Testosterone Concentrations. Molter CM, Fontenot DK, Terrell SP.J Avian Med Surg. 2015 Sep;29(3):224-30. doi: 10.1647/2014-041. PMID: 26378669 </br>7:Location and removal of deslorelin acetate implants in female African lions (Panthera leo). Moresco A, Dadone L, Arble J, Klaphake E, Agnew DW.J Zoo Wildl Med. 2014 Jun;45(2):397-401. PMID: 25000706 </br>8:Effect of Postbreeding Intramuscular Administration of Deslorelin Acetate on Plasma LH and Progesterone Concentrations and Conception Rate in Mares. Kino S, Osawa T, Mizuno S, Watanabe G, Taya K, Izaike Y.J Equine Sci. 2014;25(1):23-7. doi: 10.1294/jes.25.23. Epub 2014 Apr 22. PMID: 24834010 Free PMC Article</br>9:Effectiveness of deslorelin acetate subcutaneous implantation in a domestic queen with after-spaying urinary incontinence. Pisu MC, Veronesi MC.J Feline Med Surg. 2014 Apr;16(4):366-8. doi: 10.1177/1098612X13498250. Epub 2013 Jul 19. PMID: 23873046 </br>10:Evaluation of the efficacy and safety of single administration of 4.7-mg deslorelin acetate implants on egg production and plasma sex hormones in Japanese quail (Coturnix coturnix japonica). Petritz OA, Sanchez-Migallon Guzman D, Paul-Murphy J, Fecteau K, Mete A, Kass PH, Hawkins MG.Am J Vet Res. 2013 Feb;74(2):316-23. doi: 10.2460/ajvr.74.2.316. Erratum in: Am J Vet Res. 2013 Mar;74(3):490. PMID: 23363360 |
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