Desmethoxyyangonin

• CAT Number: I001929
• CAS Number: 15345-89-8
• Molecular Formula: C14H12O3
• Molecular Weight: 228.24
• Purity: ≥95%
• Target: Monoamine Oxidase
• Solubility: 10 mM in DMSO
• Storage: Store at -20℃
• IUPAC Name: 4-methoxy-6-[(E)-2-phenylethenyl]pyran-2-one
• InChI: InChI=1S/C14H12O3/c1-16-13-9-12(17-14(15)10-13)8-7-11-5-3-2-4-6-11/h2-10H,1H3/b8-7+
• InChIKey: DKKJNZYHGRUXBS-BQYQJAHWSA-N
• SMILES: COC1=CC(=O)OC(=C1)C=CC2=CC=CC=C2

Desmethoxyyangonin (Cat.No:I001929) is a natural compound found in the Kava plant (Piper methysticum). It exhibits anxiolytic and sedative properties, making it a key contributor to the calming effects of Kava. Desmethoxyyangonin acts on the central nervous system, promoting relaxation and reducing anxiety. Further research is ongoing to explore its potential therapeutic applications.

Reference

[1]. Uebelhack R, et al. Inhibition of platelet MAO-B by kava pyrone-enriched extract from Piper methysticum Forster (kava-kava). Pharmacopsychiatry. 1998 Sep;31(5):187-92.

[2]. Baum SS, et al. Effect of kava extract and individual kavapyrones on neurotransmitter levels in the nucleus accumbens of rats. Prog Neuropsychopharmacol Biol Psychiatry. 1998 Oct;22(7):1105-20.

[3]. Ma Y, et al. Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23. Drug Metab Dispos. 2004 Nov;32(11):1317-24.