For research use only. Not for therapeutic Use.
Desmethyl ferroquine (Cat No.:I016815) is the major active metabolite of Ferroquine. Ferroquine is an antimalarial. Desmethyl ferroquine significantly inhibits Chloroquine-sensitive and Chloroquine-resistant Plasmodium falciparum strains P. falciparum.
| Catalog Number | I016815 |
| CAS Number | 903546-18-9 |
| Molecular Formula | C₂₂H₂₂ClFeN₃ |
| Purity | ≥95% |
| Storage | Store at -20°C |
| IUPAC Name | 7-chloro-N-[[2-(methylaminomethyl)cyclopenta-2,4-dien-1-yl]methyl]quinolin-4-amine;cyclopenta-1,3-diene;iron(2+) |
| InChI | InChI=1S/C17H17ClN3.C5H5.Fe/c1-19-10-12-3-2-4-13(12)11-21-16-7-8-20-17-9-14(18)5-6-15(16)17;1-2-4-5-3-1;/h2-9,19H,10-11H2,1H3,(H,20,21);1-5H;/q2*-1;+2 |
| InChIKey | AKDMMOAFGKYNKP-UHFFFAOYSA-N |
| SMILES | CNCC1=CC=C[C-]1CNC2=C3C=CC(=CC3=NC=C2)Cl.[CH-]1C=CC=C1.[Fe+2] |
| Reference | [1]. Supan C, et al. Pharmacokinetics of ferroquine, a novel 4-aminoquinoline, in asymptomatic carriers of Plasmodium falciparum infections. Antimicrob Agents Chemother. 2012 Jun;56(6):3165-73. |
