Desmethyl Nintedanib

• CAT Number: C000150
• CAS Number: 894783-61-0
• Molecular Formula: C₃₀H₃₁N₅O₄
• Molecular Weight: 525.6
• Purity: ≥95%
• Synonyms: Nintedanib Impurity G; 2,3-Dihydro-3-[[[4-[[(4-methyl-1-piperazinyl)acetyl]amino]phenyl] amino]phenylmethylene]-2-oxo-methyl Ester-1H-indole-6-carboxylic Acid; (Z)-Methyl 3-(((4-(2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
• Solubility: DMSO (Slightly), Methanol (Slightly, Heated)
• Appearance: Light Yellow to Yellow Solid
• Storage: 4°C

Desmethyl Nintedanib(CAT: C000150) is a significant compound in the field of pharmaceutical chemistry and drug development. Its action method involves being a metabolite of Nintedanib, a tyrosine kinase inhibitor used for the treatment of idiopathic pulmonary fibrosis and other fibrotic diseases. In pharmaceutical research, Desmethyl Nintedanib is of interest as it can aid in understanding the metabolic pathways and pharmacokinetics of Nintedanib in the human body.

Reference

Roth, G., et al.: J. Med. Chem., 52, 4466 (2009);