For research use only. Not for therapeutic Use.
Desmethyl-VS-5584 Hydrochloride (Cat No.: I040054) is a potent and selective dual inhibitor of PI3K and mTOR, key signaling pathways involved in cancer progression and resistance mechanisms. As a derivative of VS-5584, it exhibits strong antiproliferative activity against tumor cells while sparing normal cells. It is widely used in oncology research to study autophagy, apoptosis, and targeted therapy resistance. Its hydrochloride form enhances solubility for in vitro and in vivo applications, making it valuable for drug development and cancer disease research.
| Synonyms | 5-(2-morpholin-4-yl-9-propan-2-ylpurin-6-yl)pyrimidin-2-amine;dihydrochloride |
| Molecular Formula | C16H22Cl2N8O |
| Purity | ≥95% |
| InChI | InChI=1S/C16H20N8O.2ClH/c1-10(2)24-9-20-13-12(11-7-18-15(17)19-8-11)21-16(22-14(13)24)23-3-5-25-6-4-23;;/h7-10H,3-6H2,1-2H3,(H2,17,18,19);2*1H |
| InChIKey | YPVQZHWMNYWOBJ-UHFFFAOYSA-N |
| SMILES | CC(C)N1C=NC2=C(N=C(N=C21)N3CCOCC3)C4=CN=C(N=C4)N.Cl.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
