For research use only. Not for therapeutic Use.
Derivative of YM-298198 (Axon 1260), a selective and noncompetitive mGluR1 antagonist
KEYWORDS: Desmethyl YM 298198 hydrochloride | 299901-57-8 | 1177767-57-5 | Axon 1259 | mGluR1 antagonist | Supplier | Axon1259 | YM298198 | desmethyl | mGluR1
Catalog Number | I010556 |
CAS Number | 1177767-57-5 |
Molecular Formula | C17H20N4OS.HCl |
Purity | ≥95% |
IUPAC Name | 7-amino-N-cyclohexyl-1-methyl-[1,3]thiazolo[3,2-a]benzimidazole-2-carboxamide;hydrochloride |
InChI | InChI=1S/C17H20N4OS.ClH/c1-10-15(16(22)19-12-5-3-2-4-6-12)23-17-20-13-8-7-11(18)9-14(13)21(10)17;/h7-9,12H,2-6,18H2,1H3,(H,19,22);1H |
SMILES | CC1=C(SC2=NC3=C(N12)C=C(C=C3)N)C(=O)NC4CCCCC4.Cl |
Reference | Kohara et al. Radioligand binding properties and pharmacological characterization of 6-Amino-N-cyclohexyl-N,3-dimethyl-thiazolo[3,2-a]-benzimidazole-2-carboxamide (YM-298198). J. Pharmacol. Exp. Ther. 2005, 315, 163. |