For research use only. Not for therapeutic Use.
Paroxetine (Item No. <span class=/itemid/>14998</span>) is a potent, selective serotonin reuptake inhibitor (K<sub>i</sub> = 0.72 nM) that has been used in cases of depression and anxiety disorder. Desmethylene paroxetine is a major urinary metabolite of paroxetine. This compound may be used in urine drug testing applications involving paroxetine toxicology or forensic analysis.
| Catalog Number | R065121 |
| CAS Number | 1394861-12-1 |
| Synonyms | 4-[[(3S,4R)-4-(4-fluorophenyl)-3-piperidinyl]methoxy]-1,2-benzenediol, monohydrochloride |
| Molecular Formula | C18H20FNO3 • HCl |
| Purity | ≥95% |
| Target | Drug Metabolite |
| Storage | -20°C |
| InChI | InChI=1S/C18H20FNO3.ClH/c19-14-3-1-12(2-4-14)16-7-8-20-10-13(16)11-23-15-5-6-17(21)18(22)9-15;/h1-6,9,13,16,20-22H,7-8,10-11H2;1H/t13-,16-;/m0./s1 |
| InChIKey | GIPUDSSHAJOHQK-LINSIKMZSA-N |
| SMILES | FC1=CC=C([C@H]2[C@H](COC3=CC(O)=C(O)C=C3)CNCC2)C=C1.Cl |
| Reference | 1.Mattson, R.J.,Catt, J.D.,Denhart, D.J., et al. Conformationally restricted homotryptamines. 2. Indole cyclopropylmethylamines as selective serotonin reuptake inhibitors. Journal of Medicinal Chemistry 48(19), 6023-6034 (2005). |
