Desmopressin Acetate

• CAT Number: P000412
• CAS Number: 62288-83-9
• Molecular Formula: C48H68N14O14S2
• Molecular Weight: 1129.27
• Purity: 98%
• Synonyms: DDAVP
• Target: Vasopressin Receptor
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• Analysis method: HPLC
• IUPAC Name: acetic acid;N-[1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
• InChI: InChI=1S/C46H64N14O12S2.C2H4O2/c47-35(62)15-14-29-40(67)58-32(22-36(48)63)43(70)59-33(45(72)60-18-5-9-34(60)44(71)56-28(8-4-17-52-46(50)51)39(66)53-23-37(49)64)24-74-73-19-16-38(65)54-30(21-26-10-12-27(61)13-11-26)41(68)57-31(42(69)55-29)20-25-6-2-1-3-7-25;1-2(3)4/h1-3,6-7,10-13,28-34,61H,4-5,8-9,14-24H2,(H2,47,62)(H2,48,63)(H2,49,64)(H,53,66)(H,54,65)(H,55,69)(H,56,71)(H,57,68)(H,58,67)(H,59,70)(H4,50,51,52);1H3,(H,3,4)
• InChIKey: MLSVJHOYXJGGTR-UHFFFAOYSA-N
• SMILES: CC(=O)O.C1CC(N(C1)C(=O)C2CSSCCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC (C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C (C=C4)O)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)N

Desmopressin acetate is a synthetic analog of vasopressin (antidiuretic hormone, ADH) used primarily to treat conditions related to excessive urination or bleeding disorders. It mimics the action of vasopressin by increasing water reabsorption in the kidneys, thus reducing urine output. It is commonly prescribed for conditions like diabetes insipidus, nocturnal enuresis (bedwetting), and for managing polyuria in certain patients. Desmopressin is also used to treat mild hemophilia A and von Willebrand disease, as it promotes the release of stored factor VIII and von Willebrand factor, improving clot formation. Its targeted action makes it a valuable therapeutic agent for both renal and bleeding disorders.