For research use only. Not for therapeutic Use.
Desthiobiotin-Iodoacetamide can be used as an ADC Linker. Desthiobiotin-Iodoacetamide also acts as a probe used to label the the Oridonin (HY-N0004)-treated cell lysis[1].
| Catalog Number | I042058 |
| CAS Number | 2924824-04-2 |
| Synonyms | N-[2-[(2-iodoacetyl)amino]ethyl]-6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanamide |
| Molecular Formula | C14H25IN4O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C14H25IN4O3/c1-10-11(19-14(22)18-10)5-3-2-4-6-12(20)16-7-8-17-13(21)9-15/h10-11H,2-9H2,1H3,(H,16,20)(H,17,21)(H2,18,19,22)/t10-,11+/m0/s1 |
| InChIKey | ASKKBTGJVCEXOA-WDEREUQCSA-N |
| SMILES | CC1C(NC(=O)N1)CCCCCC(=O)NCCNC(=O)CI |
| Reference | [1]. Zhang Y, et al. Oridonin acts as a novel senolytic by targeting glutathione S-transferases to activate the ROS-p38 signaling axis in senescent cells. Chem Commun (Camb). 2022 Nov 29;58(95):13250-13253. |
