Deterenol free base

For research use only. Not for therapeutic Use.

  • CAT Number: I025947
  • CAS Number: 7376-66-1
  • Molecular Formula: C11H17NO2
  • Molecular Weight: 195.26
  • Purity: ≥95%
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Deterenol Free Base (Cat.No:I025947) is a beta-adrenoceptor agonist. It is an effective nonmydriatic and nonmiotic hypotensive agent, which can be used in antiglaucoma treatment.


Catalog Number I025947
CAS Number 7376-66-1
Synonyms

Deterenol Free Base; BRN2098796; BRN-2098796; BRN 2098796

Molecular Formula C11H17NO2
Purity ≥95%
Solubility To be determined
Appearance Solid powder
Storage Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
IUPAC Name 4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenol
InChI InChI=1S/C11H17NO2/c1-8(2)12-7-11(14)9-3-5-10(13)6-4-9/h3-6,8,11-14H,7H2,1-2H3
InChIKey MPCPSVWSWKWJLO-UHFFFAOYSA-N
SMILES CC(C)NCC(C1=CC=C(C=C1)O)O
Reference

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2: Venhuis B, Keizers P, van Riel A, de Kaste D. A cocktail of synthetic stimulants found in a dietary supplement associated with serious adverse events. Drug Test Anal. 2014 Jun;6(6):578-81. doi: 10.1002/dta.1664. Epub 2014 May 6. PMID: 24802503.
3: Mercader J, Wanecq E, Chen J, Carpéné C. Isopropylnorsynephrine is a stronger lipolytic agent in human adipocytes than synephrine and other amines present in Citrus aurantium. J Physiol Biochem. 2011 Sep;67(3):443-52. doi: 10.1007/s13105-011-0078-2. Epub 2011 Feb 19. PMID: 21336650.
4: Anderson WG. The sympathomimetic activity of N-isopropyloctopamine in vitro. J Pharmacol Exp Ther. 1983 Jun;225(3):553-8. PMID: 6306210.
5: Deeg MA, Graeff RM, Walseth TF, Goldberg ND. A Ca2+-linked increase in coupled cAMP synthesis and hydrolysis is an early event in cholinergic and beta- adrenergic stimulation of parotid secretion. Proc Natl Acad Sci U S A. 1988 Nov;85(21):7867-71. doi: 10.1073/pnas.85.21.7867. PMID: 2460856; PMCID: PMC282298.
6: Spearman TN, Durham JP, Butcher FR. The role of cyclic AMP in the regulation of exocytosis in the rat parotid gland: evidence obtained with the isoproterenol analog PI-39. J Cyclic Nucleotide Res. 1982;8(4):225-34. PMID: 6187786.

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