Dexamethasone 21-Palmitate

• CAT Number: R046909
• CAS Number: 14899-36-6
• Molecular Formula: C38H59FO6
• Molecular Weight: 630.88
• Purity: ≥95%
• Synonyms: (11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxohexadecyl)oxy]pregna-1,4-diene-3,20-dione; Dexamethasone Palmitate; Limethason; Limethasone; Lipotalon
• Storage: Store at -20°C
• IUPAC Name: [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] hexadecanoate
• InChI: InChI=1S/C38H59FO6/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-34(43)45-26-33(42)38(44)27(2)23-31-30-20-19-28-24-29(40)21-22-35(28,3)37(30,39)32(41)25-36(31,38)4/h21-22,24,27,30-32,41,44H,5-20,23,25-26H2,1-4H3/t27-,30+,31+,32+,35+,36+,37+,38+/m1/s1
• InChIKey: WDPYZTKOEFDTCU-WDJQFAPHSA-N
• SMILES: CCCCCCCCCCCCCCCC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)O

Dexamethasone 21-Palmitate(CAT: R046909) is a lipophilic ester derivative of dexamethasone, a potent synthetic corticosteroid. This esterified form enhances the solubility of dexamethasone in lipid environments, allowing for prolonged drug release and improved tissue penetration, particularly in localized treatments. Dexamethasone 21-Palmitate retains the anti-inflammatory, immunosuppressive, and anti-allergic properties of the parent compound but is typically used in formulations designed for sustained action, such as topical or injectable preparations. It is employed in the management of various inflammatory conditions, including skin disorders, joint inflammation, and ocular conditions, where controlled and localized corticosteroid activity is beneficial.