Dexamethasone Phosphate

• CAT Number: R054237
• CAS Number: 312-93-6
• Molecular Formula: C22H30FO8P
• Molecular Weight: 472.446
• Purity: ≥95%
• Synonyms: (11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)pregna-1,4-diene-3,20-dione; 9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-Phosphate; Betnelan Phosphate; Dexamethasone 21-Dihydrogen Phosphate; Dexamethasone 21-P
• Target: Vitamin D Related/Nuclear Receptor
• Storage: -20°C
• IUPAC Name: [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] dihydrogen phosphate
• InChI: InChI=1S/C22H30FO8P/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30)/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
• InChIKey: VQODGRNSFPNSQE-CXSFZGCWSA-N
• SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)(O)O)O)C)O)F)C

Dexamethasone Phosphate is a synthetic glucocorticoid used for its potent anti-inflammatory and immunosuppressant properties. As a phosphate ester of dexamethasone, it is water-soluble, allowing for rapid absorption and onset of action when administered intravenously or intramuscularly. It is widely used in treating conditions such as severe allergies, asthma, autoimmune disorders, and as part of chemotherapy regimens to reduce inflammation and prevent nausea. Dexamethasone Phosphate is also employed in managing cerebral edema and reducing swelling associated with brain tumors or injuries, making it a versatile therapeutic agent.