Dexpramipexole

For research use only. Not for therapeutic Use.

  • CAT Number: I000259
  • CAS Number: 104632-28-2
  • Molecular Formula: C10H17N3S
  • Molecular Weight: 211.33
  • Purity: ≥95%
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Dexpramipexole(CAT: I000259) is the R(+) enantiomer of pramipexole, originally developed as a neuroprotective agent. Unlike its S(-) enantiomer, which is used as a dopamine D2/D3 receptor agonist for treating Parkinson’s disease and restless legs syndrome, dexpramipexole lacks significant dopaminergic activity. Instead, it is known for its ability to reduce oxidative stress and mitochondrial dysfunction, providing potential neuroprotection. Dexpramipexole has been investigated for treating amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases due to its role in preserving neuronal health. It remains a promising compound in neuroprotection and neurodegenerative disease research.


CAS Number 104632-28-2
Synonyms

N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine

Molecular Formula C10H17N3S
Purity ≥95%
Target Neuronal Signaling
Solubility 10 mM in DMSO
Storage Store at -20°C
IUPAC Name (6R)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
InChI InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m1/s1
InChIKey FASDKYOPVNHBLU-SSDOTTSWSA-N
SMILES CCCN[C@@H]1CCC2=C(C1)SC(=N2)N

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