Dextran sulfate sodium

For research use only. Not for therapeutic Use.

  • CAT Number: M144090
  • CAS Number: 9011-18-1
  • Purity: ≥95%
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Dextran sulfate sodium (DSS)(Cat No.:M144090)is a sulfated polysaccharide derived from dextran, composed of glucose units with sulfate ester groups and sodium counterions. It is highly water-soluble and negatively charged, making it useful in a range of biomedical and research applications. DSS is most notably used to induce colitis in experimental animal models, mimicking inflammatory bowel disease (IBD) for pathophysiological and therapeutic studies. It also functions as an anticoagulant, antiviral agent, and molecular weight modulator in biochemical research. DSS is available in defined molecular weights and should be handled under sterile conditions.


CAS Number 9011-18-1
Synonyms

Dextran sulfate sodium salt

Purity ≥95%
Target Anti-infection
Solubility Soluble in water
Storage Store at 0-8°C
Reference

1.B Caughey.; GJ Raymond. Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells. Journal of virology. 1993, 67, (2), 643-650.<br />
2.CK Lee.; SI Sandler. Vancomycin partitioning in aqueous two-phase systems: Effects of pH, salts, and an affinity ligand. Biotechnology and bioengineering. 1990, 35, (4), 408-416.

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