For research use only. Not for therapeutic Use.
Dextran sulfate sodium (DSS) (Cat No.: M144090)is a polysaccharide compound commonly used in laboratory research to induce experimental colitis in animal models. It works by disrupting the intestinal epithelial barrier, leading to inflammation and mimicking conditions like inflammatory bowel disease (IBD) in humans. DSS is often used in studies to investigate the pathogenesis of colitis, test potential therapeutic agents, and understand immune responses in the gut. While it induces acute inflammation, it is valuable in preclinical models for exploring IBD treatments.
| Catalog Number | M144090 |
| CAS Number | 9011-18-1 |
| Synonyms | Dextran sulfate sodium salt |
| Purity | ≥95% |
| Target | Anti-infection |
| Solubility | Soluble in water |
| Storage | Store at 0-8°C |
| Reference | 1.B Caughey.; GJ Raymond. Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells. Journal of virology. 1993, 67, (2), 643-650.<br /> |
