Dextromethorphan hydrobromide

• CAT Number: I001027
• CAS Number: 125-69-9
• Molecular Formula: C18H26BrNO
• Molecular Weight: 352.316
• Purity: ≥95%
• Target: Others
• Solubility: 40 mM in water ；
• Storage: Store at 4°C
• InChI: InChI=1S/C18H25NO.BrH/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H/t15-,17+,18+;/m1./s1
• InChIKey: MISZALMBODQYFT-URVXVIKDSA-N
• SMILES: CN1CCC23CCCCC2C1CC4=C3C=C(C=C4)OC.Br

Dextromethorphan hydrobromide(CAT: I001027) is a medication used as a cough suppressant. Dextromethorphan hydrobromide works by decreasing the urge to cough by acting on the cough center in the brain. It is used to treat coughs that are non-productive (do not produce phlegm or mucus) and is often found in over-the-counter cough and cold medications.

Reference

[1]. Schwartz, A.R., A.F. Pizon, and D.E. Brooks, Dextromethorphan-induced serotonin syndrome. Clin Toxicol (Phila), 2008. 46(8): p. 771-3.

[2]. Shin, E.J., et al., Dextromethorphan attenuates trimethyltin-induced neurotoxicity via sigma1 receptor activation in rats. Neurochem Int, 2007. 50(6): p. 791-9.

[3]. Shin, E.J., et al., The dextromethorphan analog dimemorfan attenuates kainate-induced seizures via sigma1 receptor activation: comparison with the effects of dextromethorphan. Br J Pharmacol, 2005. 144(7): p. 908-18.