DFMTI

• CAT Number: I005193
• CAS Number: 864864-86-8
• Molecular Formula: C20H18F2N4O
• Molecular Weight: 368.38
• Purity: ≥95%
• Target: mGluR1 Receptors Selective Antagonist
• IUPAC Name: 5-[1-(2,4-difluorophenyl)-5-methyltriazol-4-yl]-2-propan-2-yl-3H-isoindol-1-one
• InChI: InChI=1S/C20H18F2N4O/c1-11(2)25-10-14-8-13(4-6-16(14)20(25)27)19-12(3)26(24-23-19)18-7-5-15(21)9-17(18)22/h4-9,11H,10H2,1-3H3
• InChIKey: KKZVYGIANGOHBS-UHFFFAOYSA-N
• SMILES: CC1=C(N=NN1C2=C(C=C(C=C2)F)F)C3=CC4=C(C=C3)C(=O)N(C4)C(C)C

DFMTI (2,4-Difluoro-5-(trifluoromethyl)-1H-imidazole)（Cat No.:I005193）is a high-purity heterocyclic compound used in advanced pharmaceutical and chemical research. This molecule features an imidazole ring substituted with two fluorine atoms and a trifluoromethyl group, making it a versatile intermediate in the synthesis of bioactive molecules, including potential drug candidates. Its unique structure offers selective reactivity, facilitating various chemical transformations. DFMTI is essential for precise synthetic applications, supporting the development of novel therapeutic agents and contributing to advancements in medicinal chemistry and innovative research efforts.

Reference

[1]. Cho HP et al. A novel class of succinimide-derived negative allosteric modulators of metabotropic glutamate receptor subtype 1 provides insight into a disconnect in activity between the rat and human receptors. ACS Chem Neurosci. 2014 Jul 16;5(7):597-610.