DGAT1-IN-1

• CAT Number: I001744
• CAS Number: 1449779-49-0
• Molecular Formula: C30H28F3N3O4
• Molecular Weight: 551.56
• Purity: ≥95%
• Synonyms: 2-((1r,4r)-4-(4-(2-((4-(trifluoromethoxy)benzyl)carbamoyl)imidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid
• Target: Acyltransferase
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IC50: < 10 nM
• IUPAC Name: 2-[4-[4-[2-[[4-(trifluoromethoxy)phenyl]methylcarbamoyl]imidazo[1,2-a]pyridin-6-yl]phenyl]cyclohexyl]acetic acid
• InChI: InChI=1S/C30H28F3N3O4/c31-30(32,33)40-25-12-3-20(4-13-25)16-34-29(39)26-18-36-17-24(11-14-27(36)35-26)23-9-7-22(8-10-23)21-5-1-19(2-6-21)15-28(37)38/h3-4,7-14,17-19,21H,1-2,5-6,15-16H2,(H,34,39)(H,37,38)
• InChIKey: KFGSQOIWOCDWAS-UHFFFAOYSA-N
• SMILES: C1CC(CCC1CC(=O)O)C2=CC=C(C=C2)C3=CN4C=C(N=C4C=C3)C(=O)NCC5=CC=C(C=C5)OC(F)(F)F

DGAT1-IN-1(CAT: I001744) is a potent and selective inhibitor of Diacylglycerol O-acyltransferase 1 (DGAT1), an enzyme critical for triglyceride synthesis and lipid metabolism. By targeting DGAT1, this compound plays a significant role in modulating lipid homeostasis, making it valuable for research into metabolic disorders, obesity, and type 2 diabetes. DGAT1-IN-1 is widely utilized in pharmaceutical and biochemical studies to investigate pathways regulating fat storage, energy balance, and lipid-associated diseases. Known for its specificity and effectiveness, DGAT1-IN-1 is an essential tool in both academic and industrial research, providing insights into therapeutic targets for metabolic disease management.