DHODH-IN-17

• CAT Number: M134579
• CAS Number: 16344-26-6
• Molecular Formula: C12H9ClN2O2
• Molecular Weight: 248.67
• Purity: ≥95%
• Synonyms: 2-(4-chloroanilino)pyridine-3-carboxylic acid
• InChI: InChI=1S/C12H9ClN2O2/c13-8-3-5-9(6-4-8)15-11-10(12(16)17)2-1-7-14-11/h1-7H,(H,14,15)(H,16,17)
• InChIKey: YEXIXVLEDGNAKM-UHFFFAOYSA-N
• SMILES: C1=CC(=C(N=C1)NC2=CC=C(C=C2)Cl)C(=O)O

DHODH-IN-17, a 2-anilino nicotinic acid, is a human DHODH inhibitor (IC50=0.40 μM). DHODH-IN-17 can be used for theresearch of acute myeloid leukemia (AML)[1].
DHODH-IN-17, a 2-anilino nicotinic acid, is a human DHODH inhibitor with an IC50 value of 0.40 μM[1].

Reference

[1]. Lewis TA, et al. Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia. ACS Med Chem Lett. 2016;7(12):1112-1117.