For research use only. Not for therapeutic Use.
(DHQ)₂PYR(CAT: M098590), or Bis(dihydroquinidine) pyridine, is a chiral catalyst derived from dihydroquinidine and pyridine. It is widely used in asymmetric synthesis, particularly in Sharpless asymmetric dihydroxylation reactions, which involve adding two hydroxyl groups across a double bond with high stereocontrol. The two dihydroquinidine units in this ligand provide chiral centers, while the pyridine core stabilizes the structure, making it highly effective for enantioselective transformations. This ligand is valuable in producing enantiomerically pure compounds, a crucial aspect of pharmaceutical and fine chemical synthesis, where chirality directly impacts biological activity. Its high enantioselectivity and effectiveness in catalytic amounts make (DHQ)₂PYR a popular choice in organic synthesis, especially for generating optically active alcohols.
Catalog Number | M098590 |
CAS Number | 149820-65-5 |
Molecular Formula | C56H60N6O4 |
Purity | ≥95% |
Storage | Desiccate at RT |