For research use only. Not for therapeutic Use.
Diacylglycerol Acyltransferase Inhibitor-1 (CAT: I019751) is a potent and selective inhibitor of diacylglycerol acyltransferase 1 (DGAT-1), an enzyme essential for triglyceride biosynthesis. By blocking DGAT-1 activity, this compound reduces triglyceride formation and lipid accumulation, making it a valuable tool for studying metabolic disorders such as obesity, type 2 diabetes, and non-alcoholic fatty liver disease (NAFLD). DGAT-1 Inhibitor-1 is widely used in research to elucidate lipid metabolism pathways and develop novel therapeutic strategies targeting dyslipidemia and associated metabolic syndromes. Its specificity and efficacy enable detailed exploration of triglyceride homeostasis and its systemic effects.
| Catalog Number | I019751 |
| CAS Number | 1610800-25-3 |
| Molecular Formula | C₂₁H₂₃N₅O₂ |
| Purity | ≥95% |
| Target | Acyltransferase |
| IUPAC Name | 4-amino-6-(7-cyclopropyl-1-propylindol-5-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one |
| InChI | InChI=1S/C21H23N5O2/c1-2-6-25-7-5-14-10-15(11-16(18(14)25)13-3-4-13)26-8-9-28-20-17(21(26)27)19(22)23-12-24-20/h5,7,10-13H,2-4,6,8-9H2,1H3,(H2,22,23,24) |
| InChIKey | ZRAUYWHLGWICJK-UHFFFAOYSA-N |
| SMILES | CCCN1C=CC2=CC(=CC(=C21)C3CC3)N4CCOC5=NC=NC(=C5C4=O)N |
