Diazaborine

• CAT Number: I006477
• CAS Number: 22959-81-5
• PubChem Substance ID: 481709
• Molecular Formula: C₁₄H₁₃BN₂O₃S
• Molecular Weight: 300.14
• Purity: 97%
• Synonyms: 1,2-Dihydro-1-hydroxy-2-(p-tolylsulfonyl)-2,3,1-benzodiazaborine; 1,2-Dihydro-1-hydroxy-2-(p-tosyl)-2,3,1-benzo[e]diazaborine;1,2-Dihydro-1-hydroxy-2-[(4-methylphenyl)sulfonyl]-2,3,1-benzodiazaborine
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Store at RT
• IUPAC Name: 1-hydroxy-2-(4-methylphenyl)sulfonyl-2,3,1-benzodiazaborinine
• InChI: InChI=1S/C14H13BN2O3S/c1-11-6-8-13(9-7-11)21(19,20)17-15(18)14-5-3-2-4-12(14)10-16-17/h2-10,18H,1H3
• InChIKey: UQIDNSKBUXCODH-UHFFFAOYSA-N
• SMILES: B1(C2=CC=CC=C2C=NN1S(=O)(=O)C3=CC=C(C=C3)C)O

Diazaborine(CAT: I006477) is a boron-containing heterocyclic compound known for its antibacterial properties. It works by inhibiting bacterial enoyl-ACP reductase, an enzyme essential for fatty acid biosynthesis, which is critical for bacterial cell membrane production. Diazaborine has been studied for its potential in treating infections caused by Gram-negative bacteria and is of interest in research exploring new classes of antibiotics, particularly in the context of combating antibiotic resistance. Its unique boron-based structure makes it a valuable tool for studying bacterial lipid metabolism and for developing novel antimicrobial agents targeting resistant pathogens.