Dibenzoyl Thiamine

• CAT Number: I013123
• CAS Number: 299-88-7
• Molecular Formula: C₂₆H₂₆N₄O₄S
• Molecular Weight: 490.57
• Purity: ≥95%
• Target: Others
• Solubility: DMSO
• Storage: Room temperature
• IUPAC Name: [(Z)-4-[(4-amino-2-methylpyrimidin-5-yl)methyl-formylamino]-3-benzoylsulfanylpent-3-enyl] benzoate
• InChI: InChI=1S/C26H26N4O4S/c1-18(30(17-31)16-22-15-28-19(2)29-24(22)27)23(35-26(33)21-11-7-4-8-12-21)13-14-34-25(32)20-9-5-3-6-10-20/h3-12,15,17H,13-14,16H2,1-2H3,(H2,27,28,29)/b23-18-
• InChIKey: AZJUFRDUYTYIHV-NKFKGCMQSA-N
• SMILES: CC1=NC=C(C(=N1)N)CN(C=O)C(=C(CCOC(=O)C2=CC=CC=C2)SC(=O)C3=CC=CC=C3)C

Dibenzoyl thiamine（Cat No.:I013123）, also known as benfotiamine, is a synthetic derivative of thiamine (vitamin B1). It is created by replacing the thiazole ring of thiamine with a benzoyl group. Dibenzoyl thiamine is a fat-soluble compound that exhibits improved bioavailability compared to thiamine. It is commonly used as a dietary supplement to support thiamine levels in the body. Dibenzoyl thiamine is believed to have antioxidant properties and may help alleviate symptoms associated with diabetic complications such as neuropathy. It is considered safe for use as a nutritional supplement.

Reference

[1]. Heywood R, et al. Tumorigenic and toxic effect of O,S-dibenzoyl thiamine hydrochloride in prolonged dietaryadministration to rats. Toxicol Lett. 1985 Jul;26(1):53-8.