Dicentrine

For research use only. Not for therapeutic Use.

  • CAT Number: R072467
  • CAS Number: 517-66-8
  • Molecular Formula: C20H21NO4
  • Molecular Weight: 339.39
  • Purity: ≥95%
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Dicentrine is a natural product isolated from the plant Stephania epigaea Lo with antihypertensive effect. Dicentrine is an α1-adrenoceptor antagonist which has effective against human hyperplastic prostates[1].


Catalog Number R072467
CAS Number 517-66-8
Synonyms

(12S)-16,17-dimethoxy-11-methyl-3,5-dioxa-11-azapentacyclo[10.7.1.02,6.08,20.014,19]icosa-1(20),2(6),7,14,16,18-hexaene

Molecular Formula C20H21NO4
Purity ≥95%
InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17-20(25-10-24-17)19-13-9-16(23-3)15(22-2)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1
InChIKey YJWBWQWUHVXPNC-AWEZNQCLSA-N
SMILES CN1CCC2=CC3=C(C4=C2C1CC5=CC(=C(C=C54)OC)OC)OCO3
Reference

[1]. Sheu-Meei Yu, et al. Effects of dicentrine, a novel α1-adrenoceptor antagonist, on human hyperplastic prostates. European Journal of Pharmacology. 1994 Jan; 252(1):29-34.

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