Dichotomine B

• CAT Number: I043644
• CAS Number: 755036-41-0
• Molecular Formula: C14H12N2O4
• Molecular Weight: 272.26
• Purity: ≥95%
• Synonyms: 1-[(1R)-1,2-dihydroxyethyl]-9H-pyrido[3,4-b]indole-3-carboxylic acid
• InChI: InChI=1S/C14H12N2O4/c17-6-11(18)13-12-8(5-10(16-13)14(19)20)7-3-1-2-4-9(7)15-12/h1-5,11,15,17-18H,6H2,(H,19,20)/t11-/m0/s1
• InChIKey: PKSXEHHRROSXPR-NSHDSACASA-N
• SMILES: C1=CC=C2C(=C1)C3=CC(=NC(=C3N2)C(CO)O)C(=O)O

Dichotomine B, a β-Carboline alkaloid, attenuates neuroinflammatory responses in LPS/ATP-induced BV2 microglia[1].

Reference

[1]. Zhou X, et al. Dichotomine B attenuates neuroinflammatory responses via regulating TLR4/MyD88-mTOR signaling pathway in BV2 cells. Research Square. March 29th, 2022