For research use only. Not for therapeutic Use.
Diclofenac-d4 Sodium (CAS: 154523-54-3), a high-quality pharmaceutical research compound designed for advanced studies in anti-inflammatory and analgesic research. As a deuterated analog of Diclofenac sodium, it offers enhanced stability and improved pharmacokinetic properties. Diclofenac-d4 Sodium is ideal for use in pharmacological and biochemical research, providing precise and reliable data for your studies. This high-purity compound ensures consistent results, aiding in the development of novel therapies for inflammation and pain management. Trusted by leading laboratories, Diclofenac-d4 Sodium is your go-to solution for cutting-edge anti-inflammatory research. Unlock new possibilities in pain and inflammation treatment with Diclofenac-d4 Sodium, where innovation meets reliability.
| Catalog Number | S000134 |
| CAS Number | 154523-54-3 |
| Molecular Formula | C14H6D4Cl2NNaO2 |
| Purity | ≥95% |
| Target | Apoptosis |
| IUPAC Name | sodium;2-[2,3,4,5-tetradeuterio-6-(2,6-dichloroanilino)phenyl]acetate |
| InChI | InChI=1S/C14H11Cl2NO2.Na/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19;/h1-7,17H,8H2,(H,18,19);/q;+1/p-1/i1D,2D,4D,7D; |
| InChIKey | KPHWPUGNDIVLNH-QOJBZNDNSA-M |
| SMILES | [2H]C1=C(C(=C(C(=C1[2H])CC(=O)[O-])NC2=C(C=CC=C2Cl)Cl)[2H])[2H].[Na+] |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Riendeau D, et al. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor. Br J Pharmacol. 1997 May;121(1):105-17. [3]. Labib MB, et al. Design, synthesis of novel isoindoline hybrids as COX-2 inhibitors: Anti-inflammatory, analgesic activities and docking study. Bioorg Chem. 2018 Oct;80:70-80. [4]. Chiho Kudo, et al. Diclofenac Inhibits Proliferation and Differentiation of Neural Stem Cells. Biochem Pharmacol. 2003 Jul 15;66(2):289-95. |
