For research use only. Not for therapeutic Use.
Didesethyl chloroquine-d4 (CAS: 1215797-41-3), a premium pharmaceutical research compound designed for advanced antimalarial and autoimmune studies. As a deuterated analog of Didesethyl chloroquine, it offers enhanced stability and improved pharmacokinetic properties. Didesethyl chloroquine-d4 is ideal for use in pharmacological and biochemical research, providing precise and reliable data for your studies. This high-purity compound ensures consistent results, aiding in the development of novel treatments for malaria and autoimmune diseases. Trusted by leading laboratories, Didesethyl chloroquine-d4 is your go-to solution for cutting-edge research. Unlock new possibilities in antimalarial and autoimmune treatment with Didesethyl chloroquine-d4, where innovation meets reliability.
Catalog Number | S000258 |
CAS Number | 1215797-41-3 |
Molecular Formula | C14H14D4ClN3 |
Purity | ≥95% |
IUPAC Name | 4-N-(7-chloroquinolin-4-yl)-1,1,2,2-tetradeuteriopentane-1,4-diamine |
InChI | InChI=1S/C14H18ClN3/c1-10(3-2-7-16)18-13-6-8-17-14-9-11(15)4-5-12(13)14/h4-6,8-10H,2-3,7,16H2,1H3,(H,17,18)/i2D2,7D2 |
InChIKey | GYEDIFVVTRKXHP-BRVWLQDISA-N |
SMILES | [2H]C([2H])(CC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)C([2H])([2H])N |
Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Biot C, et al. Synthesis and antimalarial activity in vitro of potential metabolites of ferrochloroquine and related compounds. Bioorg Med Chem. 1999 Dec;7(12):2843-7. [3]. Essien EE, et al. Effects of chloroquine and didesethylchloroquine on rabbit myocardium and mitochondria. J Pharm Pharmacol. 1986 Jul;38(7):543-6. |