Didesmethyl Sibutramine-d6

• CAT Number: R005785
• CAS Number: 1189727-93-2
• Molecular Formula: C15H22ClN
• Molecular Weight: 257.835
• Purity: ≥95%
• Synonyms: 1-(4-Chlorophenyl)-α-(2-methylpropyl)cyclobutanemethanamine-d6; (+/-)-Didesmethylsibutramine-d6; 1-[1-(4-Chlorophenyl)cyclobutyl-d6]-3-methylbutylamine; ?1-[1-(4-Chlorophenyl)cyclobutyl-d6]-3-methylbutan-1-amine
• Storage: -20°C
• IUPAC Name: 1-[1-(4-chlorophenyl)-2,2,3,3,4,4-hexadeuteriocyclobutyl]-3-methylbutan-1-amine
• InChI: InChI=1S/C15H22ClN/c1-11(2)10-14(17)15(8-3-9-15)12-4-6-13(16)7-5-12/h4-7,11,14H,3,8-10,17H2,1-2H3/i3D2,8D2,9D2
• InChIKey: WQSACWZKKZPCHN-QYDDHRNTSA-N
• SMILES: [2H]C1(C(C(C1([2H])[2H])(C2=CC=C(C=C2)Cl)C(CC(C)C)N)([2H])[2H])[2H]

Didesmethyl Sibutramine-d6 is a deuterium-labeled form of didesmethyl sibutramine, a metabolite of sibutramine, a drug previously used as an appetite suppressant. The deuterium labeling enhances its use in mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy by improving sensitivity and precision. This labeled compound is valuable for studying the pharmacokinetics and metabolism of sibutramine, tracking the drug’s breakdown and distribution in the body. It aids in understanding metabolic pathways, optimizing formulations, and validating analytical methods for detecting sibutramine and its metabolites in biological samples.