Diethylcarbamazine citrate

• CAT Number: A000090
• CAS Number: 1642-54-2
• Molecular Formula: C10H21N3O C6H8O7
• Molecular Weight: 391.42
• Purity: ≥95%
• Storage: Store at -20°C
• IUPAC Name: N,N-diethyl-4-methylpiperazine-1-carboxamide;2-hydroxypropane-1,2,3-tricarboxylic acid
• InChI: InChI=1S/C10H21N3O.C6H8O7/c1-4-12(5-2)10(14)13-8-6-11(3)7-9-13;7-3(8)1-6(13,5(11)12)2-4(9)10/h4-9H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
• InChIKey: PGNKBEARDDELNB-UHFFFAOYSA-N
• SMILES: CCN(CC)C(=O)N1CCN(CC1)C.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

Diethylcarbamazine citrate (Cat No.:A000090) is an anthelmintic medication primarily used to treat filarial infections such as lymphatic filariasis and loiasis. It works by paralyzing and eliminating microfilariae, the immature forms of parasitic worms, in the bloodstream and lymphatic system, helping reduce symptoms and prevent disease progression. DEC is effective against various parasitic nematodes and is often used in mass drug administration programs to control filariasis in endemic regions. With a well-established safety profile, DEC is crucial for managing and preventing complications associated with filarial infections in public health initiatives.

Reference

Fernando, S. D., Rodrigo, C., & Rajapakse, S. (2011). Current Evidence on the Use of Antifilarial Agents in the Management of bancroftian Filariasis. Journal of Tropical Medicine, 2011, 1-12. doi:10.1155/2011/175941