For research use only. Not for therapeutic Use.
Diethyltoluamide-d10 is the deuterium labeled Diethyltoluamide[1]. Diethyltoluamide is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects[2].
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
| Catalog Number | R010163 |
| CAS Number | 1215576-01-4 |
| Synonyms | 3-methyl-N,N-bis(1,1,2,2,2-pentadeuterioethyl)benzamide |
| Molecular Formula | C12H7D10NO |
| Purity | ≥95% |
| InChI | InChI=1S/C12H17NO/c1-4-13(5-2)12(14)11-8-6-7-10(3)9-11/h6-9H,4-5H2,1-3H3/i1D3,2D3,4D2,5D2 |
| InChIKey | MMOXZBCLCQITDF-IZUSZFKNSA-N |
| SMILES | CCN(CC)C(=O)C1=CC=CC(=C1)C |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Lu W, et al. DEET as a feeding deterrent. PLoS One. 2017 Dec 14;12(12):e0189243. |
